MitoBloCK-11

Names

[ Name ]:
MitoBloCK-11

Biological Activity

[Description]:

MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.

[References]

References 1. Conti, M. (2018). Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy. UCLA. 2. Miyata N, et al. J Biol Chem. 2017 Mar 31;292(13):5429-5442. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₂BrN₃O₄S

[ Molecular Weight ]:
434.264

Related Compounds

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