5-Fluoronicotinic acid
Names
[ CAS No. ]:
402-66-4
[ Name ]:
5-Fluoronicotinic acid
[Synonym ]:
MFCD01318537
Nicotinic acid, 5-fluoro-
T6NJ CVQ EF
5-Fluoronicotinic acid
5-Fluoropyridine-3-carboxylic acid
5-Fluoro-3-pyridinecarboxylic acid
3-Pyridinecarboxylic acid, 5-fluoro-
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
272.2±20.0 °C at 760 mmHg
[ Melting Point ]:
199 °C
[ Molecular Formula ]:
C6H4FNO2
[ Molecular Weight ]:
141.100
[ Flash Point ]:
118.4±21.8 °C
[ Exact Mass ]:
141.022614
[ PSA ]:
50.19000
[ LogP ]:
0.41
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.542
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US5745250
- CHEMICAL NAME :
- 3-Pyridinecarboxylic acid, 5-fluoro-
- CAS REGISTRY NUMBER :
- 402-66-4
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3737542
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36/37/39
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
US5745250
[ HS Code ]:
2942000000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Chem. Pharm. Bull. 35(6) , 2280-5, (1987)
Hydrophobic chromatography and bioanalysis of some polar pyridine derivatives used as antilipolytic agents.
J. Chromatogr. A. 187(1) , 189-98, (1980)
The antilipolytic compound 5-fluoro-3-pyridinecarboxylic acid and 5-fluoro-3-hydroxymethylpyridine have been determined quantitatively in plasma (Srel = 5-7% in the concentration range 1-20 microgram/...