H-Glu-Glu-OH

Names

[ Name ]:
H-Glu-Glu-OH

[Synonym ]:
L-A-GLUTAMYL-L-GLUTAMIC ACID
H-GLU-GLU-OH
L-GLUTAMYL-L-GLUTAMIC ACID
GLU-GLU
L-Glu-L-Glu-OH
L-glutamine-L-glutamine
glutamyl-glutamicacid
Diglutamate

Biological Activity

[Description]:

Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Guo D, et, al. Duck Egg White-Derived Peptide VSEE (Val-Ser-Glu-Glu) Regulates Bone and Lipid Metabolisms by Wnt/β-Catenin Signaling Pathway and Intestinal Microbiota. Mol Nutr Food Res. 2019 Dec;63(24):e1900525.

[2]. Tamura M, et, al. The Relationship between Taste and Primary Structure of "Delicious Peptide" (Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala t) from Beef Soup. Agric. Bioi. Chem. 1989 Jul 6;52(2):319-25.

Chemical & Physical Properties

[ Density]:
1.47 g/cm3

[ Boiling Point ]:
666ºC at 760 mmHg

[ Melting Point ]:
187 ºC (分解) (ethanol )

[ Molecular Formula ]:
C₁₀H₁₆N₂O₇

[ Molecular Weight ]:
276.24300

[ Flash Point ]:
356.6ºC

[ Exact Mass ]:
276.09600

[ PSA ]:
167.02000

[ Index of Refraction ]:
1.553

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Umami-bitter interactions: the suppression of bitterness by umami peptides via human bitter taste receptor.

Biochem. Biophys. Res. Commun. 456(2) , 586-90, (2015)

Taste-taste interactions often showed in human psychophysical studies. Considering that each tastant in foodstuffs individually stimulates its responsible gustatory systems to elicit relevant taste mo...

Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.

Oncogene 33(39) , 4724-34, (2014)

Uveal melanoma (UM) is a genetically and biologically distinct type of melanoma, and once metastatic there is no effective treatment currently available. Eighty percent of UMs harbor mutations in the ...

Complex expression of the UL136 gene of human cytomegalovirus results in multiple protein isoforms with unique roles in replication.

J. Virol. 88(24) , 14412-25, (2014)

Human cytomegalovirus (HCMV) is a complex DNA virus with a 230-kb genome encoding 170 and up to 750 proteins. The upper limit of this coding capacity suggests the evolution of complex mechanisms to su...