5,6-Dihydro-5-oxoindolo[1,2-a]quinazoline-7-acetic acid

Names

[ CAS No. ]:
391670-48-7

[ Name ]:
5,6-Dihydro-5-oxoindolo[1,2-a]quinazoline-7-acetic acid

Biological Activity

[Description]:

IQA (CGP-029482) is a potent and selective protein kinase CK2 inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase

Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase

[Target]

CK2

[References]

[1]. Liu J, et al. Cascade Reaction of Morita-Baylis-Hillman Acetates with 1,1-Enediamines or Heterocyclic Ketene Aminals: Synthesis of Highly Functionalized 2-Aminopyrroles. J Org Chem. 2019 Feb 15;84(4):1797-1807.

Chemical & Physical Properties

[ Density]:
1.46

[ Molecular Formula ]:
C₁₇H₁₂N₂O₃

[ Molecular Weight ]:
292.29

[ Exact Mass ]:
292.08500

[ PSA ]:
74.83000

[ LogP ]:
2.97340

Related Compounds

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