Chlorodifluoroacetophenone

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
199.1±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₅ClF₂O

[ Molecular Weight ]:
190.574

[ Flash Point ]:
74.2±25.9 °C

[ Exact Mass ]:
189.999695

[ PSA ]:
17.07000

[ LogP ]:
2.65

[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.490

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN 3334

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

2-Chloro-2,2-difluoroacetophenone: a non-ODS-based difluorocarbene precursor and its use in the difluoromethylation of phenol derivatives.

J. Org. Chem. 71 , 9845, (2006)

A novel and non-ODS-based (ODS = ozone-depleting substance) preparation of 2-chloro-2,2-difluoroacetophenone (1) was achieved in high yield by using 2,2,2-trifluoroacetophenone as the starting materia...

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