Glucuronamide

Names

[ Name ]:
Glucuronamide

[Synonym ]:
(2S,3S,4S,5R)-3,4,5,6-Tetrahydroxytetrahydro-2H-pyran-2-carboxamide (non-preferred name)
(2S,3S,4S,5R)-3,4,5,6-Tetrahydroxytetrahydro-2H-pyran-2-carboxamide
(2S,3S,4S,5R)-2,3,4,5-Tetrahydroxy-6-oxohexanamide
Glucuronamide
EINECS 223-260-9
D-Glucuronamide

Biological Activity

[Description]:

D-Glucuronamide is the derivate of D-glucuronic acid[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. OYA H. Studies on microbial utilization of D-glucuronic acid derivatives. I. Population of D-glucuronic acid-decomposing microorganisms and its growth promoting effect. Jpn J Microbiol. 1960;4:317-326.

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
545.7±50.0 °C at 760 mmHg

[ Melting Point ]:
166-167ºC(lit.)

[ Molecular Formula ]:
C₆H₁₁NO₆

[ Molecular Weight ]:
193.155

[ Flash Point ]:
283.8±30.1 °C

[ Exact Mass ]:
193.058640

[ PSA ]:
133.24000

[ LogP ]:
-1.30

[ Appearance of Characters ]:
Powder | White to Tan

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.677

[ Water Solubility ]:
Soluble in water.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ8829200

CHEMICAL NAME :: Glucuronamide

CAS REGISTRY NUMBER :: 3789-97-7

LAST UPDATED :: 199109

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H11-N-O6

MOLECULAR WEIGHT :: 193.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,225,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5797 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,326,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,326,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4586 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,326,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NJMSAG Nagoya Journal of Medical Science. (Nagoya Univ. School of Medicine, 65 Tsuruma-cho, Showa- ku, Nagoya 466, Japan) V.2- 1927- Volume(issue)/page/year: 27,209,1965

Safety Information

[ WGK Germany ]:
2

[ RTECS ]:
LZ8829200