2,3-Dimethyl-4-nitropyridine 1-oxide

Names

[ Name ]:
2,3-Dimethyl-4-nitropyridine 1-oxide

[Synonym ]:
2,3-Dimethyl-4-nitropyridine N-Oxide
4-Nitro-2,3-lutidine
2,3-Dimethyl-4-nitropyridine-n-oxide
2,3-dimethyl-4-nitro-pyridine oxide
MFCD00065172
4-NITRO-2,3-DIMETHYLPYRIDINE N-OXIDE
4-Nitro-2,3-lutidine N-oxide
2,3-Dimethyl-4-nitropyridine-N
2,3-dimethyl-4-nitro-pyridin1-oxide
4-Nitro-2,3-Lutidine-N-Oxide
2,3-Dimethyl-4-nitropyridine 1-oxide
4-nitro-2,3-dimethylpyridine 1-oxide
3-DiMethyl-4-Nitropyridine N-Oxide
Pyridine, 2,3-dimethyl-4-nitro-, 1-oxide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
403.3±40.0 °C at 760 mmHg

[ Melting Point ]:
94-98 °C(lit.)

[ Molecular Formula ]:
C₇H₈N₂O₃

[ Molecular Weight ]:
168.150

[ Flash Point ]:
197.7±27.3 °C

[ Exact Mass ]:
168.053497

[ PSA ]:
71.28000

[ LogP ]:
0.37

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.574

[ Storage condition ]:
Room temperature.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT2807000

CHEMICAL NAME :: Pyridine, 2,3-dimethyl-4-nitro-, 1-oxide

CAS REGISTRY NUMBER :: 37699-43-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C7-H8-N2-O3

MOLECULAR WEIGHT :: 168.17

WISWESSER LINE NOTATION :: T6NJ AO B1 C1 DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1760 mg/kg/15W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - mouse Fibroblast

DOSE/DURATION :: 500 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,521,1975

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
UT2807000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Applications of TiCl₃ as a Diagnostic Reagent for the Detection of Nitro-and N-Oxide-Containing Compounds as Potentially Mutagenic Impurities Using Ultrahigh-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry. Yang RS, et al.

Org. Process Res. Dev. 20(1) , 59-64, (2015)

Chemistry & Biology Interface. El-Moselhy TF.

Chemistry and Biology 3(2) , 123-136, (2013)