3-hydroxy-9H-9-xanthenone

Names

[ Name ]:
3-hydroxy-9H-9-xanthenone

[Synonym ]:
MFCD06796485
3-hydroxy-9H-9-xanthenone
Sieber Linker; 3-Hydroxy-xanthen-9-one
3-hydroxyxanthen-9-one
3-Hydroxy-9H-xanthen-9-one
9H-Xanthen-9-one, 3-hydroxy-
Xanthen-9-one, 3-hydroxy-
Sieber Linker
Weinreb Linker

Biological Activity

[Description]:

3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . 3-Hydroxyxanthone inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs). 3-Hydroxyxanthone also inhibits TNF-alpha induced ICAM-1 expression[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Cytoskeleton >> Integrin

[References]

[1]. Madan B, et al. Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs). Bioorg Med Chem. 2002 Nov;10(11):3431-6.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
403.9±24.0 °C at 760 mmHg

[ Melting Point ]:
243 °C

[ Molecular Formula ]:
C₁₃H₈O₃

[ Molecular Weight ]:
212.20

[ Flash Point ]:
162.9±16.4 °C

[ Exact Mass ]:
212.047348

[ PSA ]:
50.44000

[ LogP ]:
2.83

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.679

[ Storage condition ]:
Store at 0°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S16-S26-S36/37/39-S37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29329900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.