Isopropyl-beta-D-thiogalactopyranoside

Names

[ CAS No. ]:
367-93-1

[ Name ]:
Isopropyl-beta-D-thiogalactopyranoside

[Synonym ]:
MFCD00063273
isopropyl beta-D-thiogalactopyranoside
Isopropyl-b-D-thiogalactopyranoside
UNII-X73VV2246B
(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-propan-2-ylsulfanyloxane-3,4,5-triol
Isopropyl β-D-1-thiogalactopyranoside
propan-2-yl 1-thio-β-D-galactopyranoside
Isopropyl 1-thio-b-D-galactopyranoside
Isopropyl-β-D-thiogalactoside
Isopropyl β-D-thiogalactoside
1-Methylethyl 1-thio-β-D-galactopyranoside
Isopropyl β-D-thiogalactopyranoside
Isopropyl-beta-D-thiogalactopyranoside
Isopropyl 1-thio-β-D-galactopyranoside
Isopropyl-β-D-thiogalactopyranoside
EINECS 206-703-0
β-D-Galactopyranoside, 1-methylethyl 1-thio-
Isopropyl β-D-thiogalactoside (IPTG)
IPTG
1-(Isopropylthio)-β-Galactopyranside

Biological Activity

[Description]:

IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Biochemical Assay Reagents

Research Areas >> Others

[In Vitro]

IPTG uptake by E. coli can be independent of the action of lactose permease, since other transport pathways are also involved. At low concentration, IPTG enters cells through lactose permease, but at high concentrations (typically used for protein induction), IPTG can enter the cells independently of lactose permease[1].

[References]

[1]. Isopropyl β-D-1-thiogalactopyranoside

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
438.4±45.0 °C at 760 mmHg

[ Melting Point ]:
105 °C

[ Molecular Formula ]:
C₉H₁₈O₅S

[ Molecular Weight ]:
238.301

[ Flash Point ]:
218.9±28.7 °C

[ Exact Mass ]:
238.087494

[ PSA ]:
115.45000

[ LogP ]:
-1.01

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.578

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H351

[ Precautionary Statements ]:
P281-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R19;R40;R66

[ Safety Phrases ]:
S23-S24/25-S36/37-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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