3-Acetyl-2,5-dichlorothiophene

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
233.9±40.0 °C at 760 mmHg

[ Melting Point ]:
37-40 °C(lit.)

[ Molecular Formula ]:
C₆H₄Cl₂OS

[ Molecular Weight ]:
195.066

[ Flash Point ]:
95.3±27.3 °C

[ Exact Mass ]:
193.935989

[ PSA ]:
45.31000

[ LogP ]:
2.82

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.576

[ Storage condition ]:
Refrigerator

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39-S22-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29349990

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synthesis and antimicrobial evaluation of new chalcones containing piperazine or 2,5-dichlorothiophene moiety.

Bioorg. Med. Chem. Lett. 17 , 5321-4, (2007)

Two new series of chalcones have been synthesized by reacting 1-(4-piperazin-1-yl-phenyl)ethanone and 1-(2,5-dichloro-3-thienyl)-1-ethanone with different substituted benzaldehydes in turn by Claisen-...

Enantioselective Synthesis of Brinzolamide (AL-4862), a New Topical Carbonic Anhydrase Inhibitor. The “DCAT Route” to Thiophenesulfonamides. Conrow RE, et al.

Org. Process Res. Dev. 3(2) , 114-20, (1999)

Facile synthesis of 2-(substituted amino)-4H-thieno [3, 2-e]-1, 3-thiazin-4-ones. Abu-El-Halawa R, et al.

Monatsh. Chem 139(10) , 1251-55, (2008)

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