3’-Deoxy-N6,N6-dimethyladenosine

Names

[ CAS No. ]:
3608-59-1

[ Name ]:
3’-Deoxy-N6,N6-dimethyladenosine

[Synonym ]:
3'-Deoxy-N,N-dimethyladenosine
Adenosine, 3'-deoxy-N,N-dimethyl-

Biological Activity

[Description]:

3’-Deoxy-N6,N6-dimethyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
565.4±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H17N5O3

[ Molecular Weight ]:
279.30

[ Flash Point ]:
295.8±32.9 °C

[ Exact Mass ]:
279.133148

[ LogP ]:
0.15

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.730