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MtUng-IN-1

Names

[ CAS No. ]:
359826-99-6

[ Name ]:
MtUng-IN-1

Biological Activity

[Description]:

MtUng-IN-1 (Compound 18a) is a Uracil DNA glycosylase of Mycobacterium (MtUng) inhibitor (IC50: 300 μM). MtUng-IN-1 can be used for research of cancers and infectious diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Kesharwani S, et al. Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur J Med Chem. 2023 Oct 5;258:115604.  

Chemical & Physical Properties

[ Molecular Formula ]:
C14H12N2O6

[ Molecular Weight ]:
304.25


Related Compounds