3',5'-DI-O-BENZOYLTHYMIDINE

Names

[ Name ]:
3',5'-DI-O-BENZOYLTHYMIDINE

[Synonym ]:
O3',O5'-Dibenzoyl-thymidin
EINECS 252-786-1
3',5'-O-dibenzoyl thymidine
O3',O5'-dibenzoyl-thymidine
3',5'-Dibenzoylthymidine
3',5'-Di-O-benzoylthymidine
Thymidine,3',5'-dibenzoate

Biological Activity

[Description]:

3’,5’-Di-O-benzoyl thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.39g/cm3

[ Molecular Formula ]:
C₂₄H₂₂N₂O₇

[ Molecular Weight ]:
450.44

[ Exact Mass ]:
450.14300

[ PSA ]:
116.69000

[ LogP ]:
2.21510

[ Index of Refraction ]:
1.636

3',5'-DI-O-BENZOYLTHYMIDINE

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Related Compounds