4-chloro-2-(trichloromethyl)quinoline

[ Density]:
1.56g/cm3

[ Boiling Point ]:
331.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₀H₅Cl₄N

[ Molecular Weight ]:
280.96500

[ Flash Point ]:
184.7ºC

[ Exact Mass ]:
278.91800

[ PSA ]:
12.89000

[ LogP ]:
4.71490

[ Index of Refraction ]:
1.655

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[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2933499090

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine.

J. Invest. Dermatol. 135(4) , 1033-42, (2015)

Keratitis-ichthyosis-deafness (KID) syndrome is an ectodermal dysplasia caused by dominant mutations of connexin26 (Cx26). Loss of Cx26 function causes nonsyndromic sensorineural deafness, without con...

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