1H-Indol-3-yl β-D-glucopyranosiduronic acid

Names

[ Name ]:
1H-Indol-3-yl β-D-glucopyranosiduronic acid

[Synonym ]:
1H-Indol-3-yl β-D-glucopyranosiduronic acid
β-D-Glucopyranosiduronic acid, 1H-indol-3-yl
MFCD00083390

Biological Activity

[Description]:

3-Indolyl-β-D-glucuronide, a chromogenic substrate for β-D-glucuronidase, employs in the detection and enumeration of E. coli, yielding a blue precipitate upon cleavage. 3-Indolyl-β-D-glucuronide in? patients' plasma act as a new indicator of renal failure[1][2].

[Related Catalog]:

Research Areas >> Others

[Target]

others

[References]

[1]. S Fujita, et al. [Evaluation of a new disk containing indoxyl-beta-D-glucuronide for rapid identification of Escherichia coli]. Rinsho Byori. 1996 Sep;44(9):895-8.

[2]. S Agatsuma, et al. Indoxyl-beta-D-glucuronide and 3-indoxyl sulfate in plasma of hemodialysis patients. Clin Nephrol. 1996 Apr;45(4):250-6.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
669.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₅NO₇

[ Molecular Weight ]:
309.271

[ Flash Point ]:
358.4±31.5 °C

[ Exact Mass ]:
309.084839

[ PSA ]:
132.24000

[ LogP ]:
-0.91

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.746

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
24/25-36-26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Rapid detection of Escherichia coli in urine samples by a new chromogenic beta-glucuronidase assay.

J. Clin. Microbiol. 27 , 778-779, (1989)

A new compound, indoxyl-beta-D-glucuronide, was assessed as a substrate for the rapid detection of Escherichia coli in urine. Incorporation of this compound into MacConkey agar allowed the direct diff...

Accumulation of indoxyl-beta-D-glucuronide in uremic serum: suppression of its production by oral sorbent and efficient removal by hemodialysis.

Nephron 74(1) , 72-8, (1996)

We identified and quantified indoxyl-beta-D-glucuronide in uremic serum and urine to determine the metabolism of indoles including indoxyl sulfate in uremic patients. Serum levels of indoxyl-beta-D-gl...

[Evaluation of a new disk containing indoxyl-beta-D-glucuronide for rapid identification of Escherichia coli].

Rinsho Byori. 44(9) , 895-8, (1996)

To establish a simple identification procedure for Escherichia coli, we developed a disk containing indoxyl-beta-D-glucuronide, the chromogenic substrate of beta-D-glucuronidase. Of 188 isolates of En...

Related Compounds

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