Cyclohexanol,1-(2-propyn-1-yl)-, 1-carbamate
Names
[ CAS No. ]:
358-52-1
[ Name ]:
Cyclohexanol,1-(2-propyn-1-yl)-, 1-carbamate
[Synonym ]:
Hexapropymate
Modirax
LF 62
Propynylcyclohexanol carbamate
Hexopropynate
Lunamin
Merinax
Esapropimato
Chemical & Physical Properties
[ Density]:
1.08g/cm3
[ Boiling Point ]:
304.6ºC at 760mmHg
[ Molecular Formula ]:
C10H15NO2
[ Molecular Weight ]:
181.23200
[ Flash Point ]:
138.5ºC
[ Exact Mass ]:
181.11000
[ PSA ]:
52.32000
[ LogP ]:
2.50820
[ Index of Refraction ]:
1.503
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FD1150000
- CHEMICAL NAME :
- Carbamic acid, 1-(2-propynyl)cyclohexyl ester
- CAS REGISTRY NUMBER :
- 358-52-1
- BEILSTEIN REFERENCE NO. :
- 3253991
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H15-N-O2
- MOLECULAR WEIGHT :
- 181.26
- WISWESSER LINE NOTATION :
- L6TJ AOVZ A2UU1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma Lungs, Thorax, or Respiration - cyanosis Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
- REFERENCE :
- MTAEEB Medical Toxicology and Adverse Drug Experience. (Adis International Ltd., Private Baq 65901, Mairangi Bay, Auckland 10, N.Z.) V.4- 1989- Volume(issue)/page/year: 4,295,1989
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 228 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Vascular - BP lowering not characterized in autonomic section Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 1,1593,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 286 mg/kg/36H-I
- TOXIC EFFECTS :
- Behavioral - coma Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- MTAEEB Medical Toxicology and Adverse Drug Experience. (Adis International Ltd., Private Baq 65901, Mairangi Bay, Auckland 10, N.Z.) V.4- 1989- Volume(issue)/page/year: 4,295,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,414,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,414,1972
Safety Information
[ HS Code ]:
2924299090
Synthetic Route
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%