(2H)Formamide

Names

[ CAS No. ]:
35692-88-7

[ Name ]:
(2H)Formamide

[Synonym ]:
(H)Formamide
C-Deuterio-formamid
d1-N,N-formamide
Formamide-1-d
Formamide-d
formamide-d1
MFCD01074135
C-deuterio-formamide

Biological Activity

[Description]:

Formamide-d1 is the deuterium labeled Formamide[1]. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
210.5±9.0 °C at 760 mmHg

[ Melting Point ]:
2-3ºC(lit.)

[ Molecular Formula ]:
CH2DNO

[ Molecular Weight ]:
46.047

[ Flash Point ]:
81.1±18.7 °C

[ Exact Mass ]:
46.027740

[ PSA ]:
43.09000

[ LogP ]:
-1.51

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.370

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H351-H360D-H373

[ Precautionary Statements ]:
P201-P260-P280-P308 + P313

[ Target Organs ]:
Blood

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
61-37/38-41

[ Safety Phrases ]:
53-23-26-36/37/39-45

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds