SARS-CoV-2 3CLpro-IN-16

Names

[ Name ]:
SARS-CoV-2 3CLpro-IN-16

Biological Activity

[Description]:

SARS-CoV-2 3CLpro-IN-16 (Compound 3a) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 2.124 μM). SARS-CoV-2 3CLpro-IN-16 binds to the active site and forms a covalent bond with Cys145 of 3CLpro[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

2.124 μM (SARS-CoV-2 3CLpro)[1]

[References]

[1]. Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₄N₂OS

[ Molecular Weight ]:
294.37

Related Compounds

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