352659-40-6

352659-40-6 structure

Name: SARS-CoV-2 3CLpro-IN-16
Chemical Name: SARS-CoV-2 3CLpro-IN-16
CAS Number: 352659-40-6
Molecular Formula: C₁₇H₁₄N₂OS
Molecular Weight: 294.37
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2023-11-04 16:23:10
Modify Date: 2025-08-27 06:54:23
SARS-CoV-2 3CLpro-IN-16 (Compound 3a) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 2.124 μM). SARS-CoV-2 3CLpro-IN-16 binds to the active site and forms a covalent bond with Cys145 of 3CLpro[1].

Name	SARS-CoV-2 3CLpro-IN-16

Description	SARS-CoV-2 3CLpro-IN-16 (Compound 3a) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 2.124 μM). SARS-CoV-2 3CLpro-IN-16 binds to the active site and forms a covalent bond with Cys145 of 3CLpro[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	2.124 μM (SARS-CoV-2 3CLpro)[1]
References	[1]. Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.

Molecular Formula	C₁₇H₁₄N₂OS
Molecular Weight	294.37