{[4-Chloro-2-methyl(2H3)phenyl]oxy}acetic acid

Names

[ CAS No. ]:
352431-14-2

[ Name ]:
{[4-Chloro-2-methyl(2H3)phenyl]oxy}acetic acid

[Synonym ]:
Acetic acid, 2-[(4-chloro-6-methylphenyl-2,3,5-d)oxy]-
{[4-Chloro-2-methyl(H)phenyl]oxy}acetic acid

Biological Activity

[Description]:

MCPA-d3 is the deuterium labeled MCPA[1]. MCPA is a phenoxy herbicide, and widely used to control annual and perennial broad leaved weeds, including poppy, thistles and docks, in crops such as cereals, rice, linseed, flax, grassland and turf[2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Munira S, et, al. Sorption and desorption of glyphosate, MCPA and tetracycline and their mixtures in soil as influenced by phosphate. J Environ Sci Health B. 2017 Dec 2;52(12):887-895.  

[3]. Kwiecien I, et, al. Biodegradable PBAT/PLA Blend with Bioactive MCPA-PHBV Conjugate Suppresses Weed Growth. Biomacromolecules. 2018 Feb 1219(2):511-520.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
327.0±27.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H6ClD3O3

[ Molecular Weight ]:
203.637

[ Flash Point ]:
151.6±23.7 °C

[ Exact Mass ]:
203.042847

[ PSA ]:
46.53000

[ LogP ]:
2.49

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.552

Related Compounds