3-Bromo-4-methoxybenzaldehyde

[ Density]:
1.522 g/cm3

[ Boiling Point ]:
108-110°C 1mm

[ Melting Point ]:
51-54 °C(lit.)

[ Molecular Formula ]:
C₈H₇BrO₂

[ Molecular Weight ]:
215.04400

[ Flash Point ]:
108-110°C/1mm

[ Exact Mass ]:
213.96300

[ PSA ]:
26.30000

[ LogP ]:
2.27020

[ Index of Refraction ]:
1.585

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Click to get detail synthetic route

Precursor

DownStream

Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines.

J. Med. Chem. 49(1) , 179-85, (2006)

A series of new 2-phenylbenzothiazoles has been synthesized on the basis of the discovery of the potent and selective in vitro antitumor properties of 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (8n...

Structure-based discovery of a boronic acid bioisostere of combretastatin A-4.

Chem. Biol. 12(9) , 1007-14, (2005)

Targeting the microtubule system represents an attractive strategy for the development of anticancer agents. In this study, we report a class of combretastatin A-4 (CA-4) analogs derivatized with a bo...

22287813

10th Internatl. Conf. on Organic Synthesis, Bangalore, India, December 1994

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