Fluo-3FF AM

Names

[ Name ]:
Fluo-3FF AM

[Synonym ]:
Acetoxymethyl ({4-[6-(acetoxymethoxy)-2,7-dichloro-3-oxo-3H-xanthen-9-yl]-2-[2-(6-{bis[2-(acetoxymethoxy)-2-oxoethyl]amino}-2,3-difluorophenoxy)ethoxy]phenyl}[2-(acetoxymethoxy)-2-oxoethyl]amino)acetate
Fluo-3FF-AM
MFCD01866560

Biological Activity

[Description]:

Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca2+ sensitive indicator (Abs/Em = 462 nm/526 nm). Fluo-3FF AM is Mg2+ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.[1]

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Gordienko DV, et al. Regulation of muscarinic cationic current in myocytes from guinea-pig ileum by intracellular Ca2+ release: a central role of inositol 1,4,5-trisphosphate receptors. Cell Calcium. 2004 Nov;36(5):367-86.

[2]. Young RC, et al. Focal sarcoplasmic reticulum calcium stores and diffuse inositol 1,4,5-trisphosphate and ryanodine receptors in human myometrium. Cell Calcium. 1999 Jul-Aug;26(1-2):69-75.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1087.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅₀H₄₆Cl₂F₂N₂O₂₃

[ Molecular Weight ]:
1151.80

[ Flash Point ]:
611.4±34.3 °C

[ Exact Mass ]:
1150.183594

[ LogP ]:
4.94

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.611

Related Compounds

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