5-Bromoindanone

Names

[ Name ]:
5-Bromoindanone

[Synonym ]:
5-Bromoindan-1-one
5-Bromo-1-indanone
1H-Inden-1-one, 5-bromo-2,3-dihydro-
1-Indanone, 5-bromo-
1H-Inden-1-one,5-bromo-2,3-dihydro
1-Indanone,5-bromo
5-bromoindane-1-one
5-Bromindan-1-on
5-bromo-2,3-dihydro-1H-indene-1-one
MFCD00082718
5-Brom-2,3-dihydro-1H-inden-1-on
5-bromo-2,3-dihydro-1H-inden-1-one
5-bromo-indanone
5-Bromoindanone

Biological Activity

[Description]:

5-Bromo-2,3-dihydro-1H-inden-1-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
303.7±31.0 °C at 760 mmHg

[ Melting Point ]:
126-129 °C(lit.)

[ Molecular Formula ]:
C₉H₇BrO

[ Molecular Weight ]:
211.06

[ Flash Point ]:
120.2±12.2 °C

[ Exact Mass ]:
209.968018

[ PSA ]:
17.07000

[ LogP ]:
2.86

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.623

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Discovery of a series of imidazo[4,5-b]pyridines with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ.

J. Med. Chem. 54 , 4219-4233, (2011)

Mining of an in-house collection of angiotensin II type 1 receptor antagonists to identify compounds with activity at the peroxisome proliferator-activated receptor-γ (PPARγ) revealed a new series of ...

Novel imidazolyl and triazolyl substituted biphenyl compounds: synthesis and evaluation as nonsteroidal inhibitors of human 17alpha-hydroxylase-C17, 20-lyase (P450 17).

Bioorg. Med. Chem. 8(6) , 1245-52, (2000)

The synthesis of a new series of P450 17 inhibitors is described. The imidazol-1-yl compounds 5 showed strong inhibition of P450 17 rat and especially human enzyme, the most active compounds being 5ax...

The identification of potent and selective imidazole-based inhibitors of B-Raf kinase.

Bioorg. Med. Chem. Lett. 16(2) , 378-381, (2006)

A novel triarylimidazole derivative, SB-590885 (33), bearing a 2,3-dihydro-1H-inden-1-one oxime substituent has been identified as a potent and extremely selective inhibitor of B-Raf kinase.