Benzyl hydroxycarbamate

Names

[ Name ]:
Benzyl hydroxycarbamate

[Synonym ]:
Carbamic acid,hydroxy-,phenylmethyl ester
N-Hydroxycarbamic Acid Benzyl Ester
N-Z-Hydroxylamine,Benzyl N-hydroxycarbamate
N-carbobenzoxyhydroxylamine
N-(Benzyloxycarbonyl)hydroxylamine
Carbamic acid, N-hydroxy-, phenylmethyl ester
N-Z-Hydroxylamine
Benzyl hydroxycarbamate
N-Cbz-hydroxylamine
MFCD00010642

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
373.4±21.0 °C at 760 mmHg

[ Melting Point ]:
65-70 °C(lit.)

[ Molecular Formula ]:
C₈H₉NO₃

[ Molecular Weight ]:
167.162

[ Flash Point ]:
179.6±22.1 °C

[ Exact Mass ]:
167.058243

[ PSA ]:
58.56000

[ LogP ]:
1.37

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.560

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FB1600000

CHEMICAL NAME :: Carbamic acid, hydroxy-, benzyl ester

CAS REGISTRY NUMBER :: 3426-71-9

BEILSTEIN REFERENCE NO. :: 1074034

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H9-N-O3

MOLECULAR WEIGHT :: 167.18

WISWESSER LINE NOTATION :: QMVO1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 800 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 151,201,1985

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
FB1600000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Inhibitors of bacterialN-succinyl-l,l-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity

Bioorg. Med. Chem. Lett. 19 , 6350-2, (2009)

A screen biased toward compounds containing zinc-binding groups (ZBG’s) delivered a number of micromolar inhibitors of DapE from Haemophilus influenzae, including l-captopril (IC 50 = 3.3 μM, K i = 1....