Benzyl hydroxycarbamate
Names
[ CAS No. ]:
3426-71-9
[ Name ]:
Benzyl hydroxycarbamate
[Synonym ]:
Carbamic acid,hydroxy-,phenylmethyl ester
N-Hydroxycarbamic Acid Benzyl Ester
N-Z-Hydroxylamine,Benzyl N-hydroxycarbamate
N-carbobenzoxyhydroxylamine
N-(Benzyloxycarbonyl)hydroxylamine
Carbamic acid, N-hydroxy-, phenylmethyl ester
N-Z-Hydroxylamine
Benzyl hydroxycarbamate
N-Cbz-hydroxylamine
MFCD00010642
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
373.4±21.0 °C at 760 mmHg
[ Melting Point ]:
65-70 °C(lit.)
[ Molecular Formula ]:
C8H9NO3
[ Molecular Weight ]:
167.162
[ Flash Point ]:
179.6±22.1 °C
[ Exact Mass ]:
167.058243
[ PSA ]:
58.56000
[ LogP ]:
1.37
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.560
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FB1600000
- CHEMICAL NAME :
- Carbamic acid, hydroxy-, benzyl ester
- CAS REGISTRY NUMBER :
- 3426-71-9
- BEILSTEIN REFERENCE NO. :
- 1074034
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C8-H9-N-O3
- MOLECULAR WEIGHT :
- 167.18
- WISWESSER LINE NOTATION :
- QMVO1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 800 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 151,201,1985
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
FB1600000
[ HS Code ]:
2924299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Bioorg. Med. Chem. Lett. 19 , 6350-2, (2009)
A screen biased toward compounds containing zinc-binding groups (ZBG’s) delivered a number of micromolar inhibitors of DapE from Haemophilus influenzae, including l-captopril (IC 50 = 3.3 μM, K i = 1....