4-Methoxy Methamphetamine Hydrochloride
Names
[ CAS No. ]:
3398-68-3
[ Name ]:
4-Methoxy Methamphetamine Hydrochloride
[Synonym ]:
p-Methoxy-N,α-dimethylphenethylamine hydrochloride
p-Methoxymethamphetamine Hydrochloride
1-(4-methoxyphenyl)-N-methylpropan-2-amine,hydrochloride
1-(4-Methoxyphenyl)-N-methyl-2-propanamine hydrochloride (1:1)
Phenethylamine, N,α-dimethyl-p-methoxy-, hydrochloride
UNII:0U3N9S2CHG
Benzeneethanamine, 4-methoxy-N,α-dimethyl-, hydrochloride (1:1)
EINECS 222-265-3
Chemical & Physical Properties
[ Boiling Point ]:
262.9ºC at 760 mmHg
[ Melting Point ]:
174 °C
[ Molecular Formula ]:
C11H18ClNO
[ Molecular Weight ]:
215.720
[ Flash Point ]:
106.6ºC
[ Exact Mass ]:
215.107697
[ PSA ]:
21.26000
[ LogP ]:
3.03850
[ Storage condition ]:
?20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH5671000
- CHEMICAL NAME :
- Phenethylamine, N,alpha-dimethyl-p-methoxy-, hydrochloride
- CAS REGISTRY NUMBER :
- 3398-68-3
- LAST UPDATED :
- 199007
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C11-H17-N-O.Cl-H
- MOLECULAR WEIGHT :
- 215.75
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,150,1948
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 63 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- PBBHAU Pharmacology, Biochemistry and Behavior. (ANKHO International Inc., P.O. Box 426, Fayetteville, NY 13066) V.1- 1973- Volume(issue)/page/year: 31,9,1988
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301 + H311 + H331-H370
[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311
[ Hazard Codes ]:
F,T
[ Risk Phrases ]:
11-23/24/25-39/23/24/25
[ Safety Phrases ]:
16-36/37-45
[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution
[ HS Code ]:
2922299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922299090
[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Forensic Sci. Int. 177(1) , 77-84, (2008)
A newly synthesized designer drug, para-methoxyethylamphetamine (PMEA) was unexpectedly detected in the postmortem specimens of fatality involving drug intoxication in 2005, Japan. For unequivocal ide...
Studies on distribution of para-methoxymethamphetamine (PMMA) designer drug in rats using gas chromatography-mass spectrometry.Leg. Med. (Tokyo.) 11 Suppl 1 , S429-30, (2009)
para-Methoxymethamphetamine (PMMA) is an abused psychedelic compound with reports of several intoxications and deaths after ingestion. However, its pharmacokinetics based on a controlled study is unkn...
New designer drug p-methoxymethamphetamine: studies on its metabolism and toxicological detection in urine using gas chromatography-mass spectrometry.J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 789(1) , 27-41, (2003)
Studies are described on the metabolism and the toxicological analysis of the new designer drug rac-p-methoxymethamphetamine (PMMA) in rat urine using gas chromatography-mass spectrometry (GC-MS). The...