2-Chloro-4-hydroxybenzonitrile

Names

[ Name ]:
2-Chloro-4-hydroxybenzonitrile

[Synonym ]:
HO(3-Cl,4-CN)Ph
2-Chloro-4-hydroxybenzonitrile
2-chloro-4-hydroxy-benzonitrile
3-chloro-4-cyano phenol
MFCD00052185
2-chloro-4-hydroxybenzenecarbonitrile
2-Chlor-4-hydroxybenzonitril
Benzonitrile, 2-chloro-4-hydroxy-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
323.2±27.0 °C at 760 mmHg

[ Melting Point ]:
160ºC (dec.)(lit.)

[ Molecular Formula ]:
C₇H₄ClNO

[ Molecular Weight ]:
153.566

[ Flash Point ]:
149.3±23.7 °C

[ Exact Mass ]:
152.998138

[ PSA ]:
44.02000

[ LogP ]:
2.48

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.611

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

[ HS Code ]:
2926909090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Novel macrocyclic C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents.

Bioorg. Med. Chem. 19(18) , 5468-79, (2011)

Novel macrocyclic C-aryl glucoside SGLT2 inhibitors were designed and synthesized. Two different synthetic routes of macrocyclization were adopted to prepare novel ansa SGLT2 inhibitors. Among the com...

An expeditious synthesis of 6-aminophenanthridines. Gug F, et al.

Tetrahedron Lett. 46(21) , 3725-27, (2005)