Ecabet

Names

[ Name ]:
Ecabet

[Synonym ]:
Ecabet
sulfodehydroabietic acid
Ecabetum
Gastrom
12-sulfodehydroabietic acid

Biological Activity

[Description]:

Ecabet sodium (TA-2711) is currently applied to some clinical gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication[1]. Ecabet sodium reduces apoptosis[2]

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Wang Y, et al. Efficacy and safety of ecabet sodium as an adjuvant therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. Helicobacter. 2014 Oct;19(5):372-81.

[2]. Rah YC, et al. Ecabet sodium alleviates neomycin-induced hair cell damage. Free Radic Biol Med. 2015 Dec;89:1176-83.

Chemical & Physical Properties

[ Density]:
1.241 g/cm3

[ Molecular Formula ]:
C₂₀H₂₈O₅S

[ Molecular Weight ]:
380.49800

[ Exact Mass ]:
380.16600

[ PSA ]:
100.05000

[ LogP ]:
5.23240

[ Index of Refraction ]:
1.562

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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