TC HSD 21

Names

[ Name ]:
TC HSD 21

Biological Activity

[Description]:

TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

IC50: 14 nM (17β-HSD3)[1]

[References]

[1]. Harada K,et al. Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):504-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₂BrNO₃S₂

[ Molecular Weight ]:
422.32

[ Exact Mass ]:
420.94400

[ PSA ]:
107.16000

[ LogP ]:
4.63410

[ Storage condition ]:
2-8℃

Related Compounds

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