Withanolide A

Names

[ Name ]:
Withanolide A

[Synonym ]:
MFCD07779143

Biological Activity

[Description]:

Withanolide A, isolated from the indian herbal drug Ashwagandha (root of Withania somnifera), could regenerate neurites and reconstruct synapses in severely damaged neurons[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Kuboyama T, et al. Neuritic regeneration and synaptic reconstruction induced by withanolide A. Br J Pharmacol. 2005 Apr;144(7):961-71.

Chemical & Physical Properties

[ Density]:
1.264

[ Boiling Point ]:
651.6±55.0 °C(Predicted)

[ Melting Point ]:
305℃ (DEC.)

[ Molecular Formula ]:
C₂₈H₃₈O₆

[ Molecular Weight ]:
470.59800

[ Exact Mass ]:
470.26700

[ PSA ]:
96.36000

[ LogP ]:
3.49540

[ Appearance of Characters ]:
white

[ Storage condition ]:
?20°C

[ Water Solubility ]:
methanol: soluble1mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Immunomodulating properties of 5,20 alpha (R)-dihydroxy-6 alpha,7 alpha-epoxy-1-oxo-(5 alpha)-whitha-2,24-dienolide and solasodine.

Planta Med. 44(1) , 32-3, (1982)

Related Compounds

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