Sulfametrole

Names

[ Name ]:
Sulfametrole

[Synonym ]:
UNII-F5AK41IPQG
sulphametrole
Sulfametrole
Benzenesulfonamide, 4-amino-N-(4-methoxy-1,2,5-thiadiazol-3-yl)-
4-sulfanilamido-3-methoxy-1,2,5-thiadiazole
Sulfametrol
N1-(4-methoxy-1,2,5-thiadiazol-3-yl)sulfanilamide
Sulfametrolum
4-Amino-N-(4-methoxy-1,2,5-thiadiazol-3-yl)benzenesulfonamide
3-Methoxy-4-(4'-aminobenzenesulfonamido)-1,2,5-thiadiazole

Biological Activity

[Description]:

Sulfametrole is an orally active and potent antibacterial. Sulfametrole can be used for infections research, such as HIV, severe pneumonia and UTIs (urinary tract infections)[1][2].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Koo Chung Hoe, et al. The Crystal and Molecular Structures of Sulfametrole. Bulletin of the Korean Chemical Society. 1982,3(1):9-13.

[2]. Vouloumanou EK, et al. Trimethoprim/sulfametrole: evaluation of the available clinical and pharmacokinetic/pharmacodynamic evidence. Int J Antimicrob Agents. 2011;38(3):197-216.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
496.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₀N₄O₃S₂

[ Molecular Weight ]:
286.33

[ Flash Point ]:
253.8±31.5 °C

[ Exact Mass ]:
286.019440

[ PSA ]:
147.05000

[ LogP ]:
1.64

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.672

Safety Information

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%