RU-TRAAK-1

Names

[ Name ]:
RU-TRAAK-1

[Synonym ]:
2-(2-Furyl)-3-{(E)-[4-hydroxy-3,5-bis(2-methyl-2-propanyl)benzylidene]amino}-4(3H)-quinazolinone
4(3H)-Quinazolinone, 3-[[(1E)-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]amino]-2-(2-furanyl)-
3-{[(E)-(3,5-Di-tert-butyl-4-hydroxyphenyl)methylene]amino}-2-(2-furyl)quinazolin-4(3H)-one

Biological Activity

[Description]:

A poorly reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2).

[References]

References 1. Su Z, et al. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5748-53. View Related Products by Target Potassium Channel

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
561.3±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₂₉N₃O₃

[ Molecular Weight ]:
443.538

[ Flash Point ]:
293.3±32.9 °C

[ Exact Mass ]:
443.220886

[ LogP ]:
6.61

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.600

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.