328034-85-1
328034-85-1 structure
- Name: RU-TRAAK-1
- Chemical Name: 3-{[(E)-(3,5-Di-tert-butyl-4-hydroxyphenyl)methylene]amino}-2-(2-furyl)quinazolin-4(3H)-one
- CAS Number: 328034-85-1
- Molecular Formula: C27H29N3O3
- Molecular Weight: 443.538
- Create Date: 2020-01-11 12:35:57
- Modify Date: 2025-09-29 11:51:11
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A poorly reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2).
| Name | 3-{[(E)-(3,5-Di-tert-butyl-4-hydroxyphenyl)methylene]amino}-2-(2-furyl)quinazolin-4(3H)-one |
|---|---|
| Synonyms |
2-(2-Furyl)-3-{(E)-[4-hydroxy-3,5-bis(2-methyl-2-propanyl)benzylidene]amino}-4(3H)-quinazolinone
4(3H)-Quinazolinone, 3-[[(1E)-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]amino]-2-(2-furanyl)- 3-{[(E)-(3,5-Di-tert-butyl-4-hydroxyphenyl)methylene]amino}-2-(2-furyl)quinazolin-4(3H)-one |
| Description | A poorly reversible TRAAK inhibitor, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2). |
|---|---|
| References | References 1. Su Z, et al. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5748-53. View Related Products by Target Potassium Channel |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 561.3±60.0 °C at 760 mmHg |
| Molecular Formula | C27H29N3O3 |
| Molecular Weight | 443.538 |
| Flash Point | 293.3±32.9 °C |
| Exact Mass | 443.220886 |
| LogP | 6.61 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.600 |