3,5-Di(trifluoromethyl)aniline

Names

[ CAS No. ]:
328-74-5

[ Name ]:
3,5-Di(trifluoromethyl)aniline

[Synonym ]:
EINECS 206-335-0
3,5-Bis(trifluoromethyl)aniline
3,5-Bis(trifluoromethyl)benzenamine
FXFFR CZ EXFFF
3,5-Di(Trifluoromethyl)Aniline
Benzenamine, 3,5-bis(trifluoromethyl)-
α,α,α,α',α',α'-Hexafluoro-3,5-xylidine
3,5-bis-trifluoromethyl-aniline
MFCD00000394
MBT-NH2

Biological Activity

[Description]:

3,5-Di(trifluoromethyl)aniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

3,5-双(三氟甲基)苯胺用于合成N-[2-羟基-1-亚萘基]-3,5-双(三氟甲基)苯胺、席夫碱和5,7-双(三氟甲基)苯胺。还用于钛催化加氢胺化反应合成N-1-苯乙基-3,5-双(三氟甲基)苯胺和N,N?-双[3,5-双(三氟甲基)苯基]硫脲, 有机催化剂。

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
175.5±40.0 °C at 760 mmHg

[ Melting Point ]:
3ºC

[ Molecular Formula ]:
C₈H₅F₆N

[ Molecular Weight ]:
229.13

[ Flash Point ]:
70.0±18.0 °C

[ Exact Mass ]:
229.032623

[ PSA ]:
26.02000

[ LogP ]:
4.12

[ Vapour Pressure ]:
1.1±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.423

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZE9800000

CHEMICAL NAME :: 3,5-Xylidine, alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-

CAS REGISTRY NUMBER :: 328-74-5

BEILSTEIN REFERENCE NO. :: 0654318

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H5-F6-N

MOLECULAR WEIGHT :: 229.14

WISWESSER LINE NOTATION :: FXFFR CZ EXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 31300 ug/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - ataxia

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,323,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,143,1954

Safety Information

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
2810

[ WGK Germany ]:
3

[ RTECS ]:
ZE9800000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29214910

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

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