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Tiaramide

Names

[ CAS No. ]:
32527-55-2

[ Name ]:
Tiaramide

[Synonym ]:
Tiaramida [INN-Spanish]
USV 2592
5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]-3H-benzothiazol-2-one
TIARAMIDE
5-chloro-3-[4-(2-hydroxyethyl)-1-piperazinyl]carbonylmethyl-2-benzothiazolinone
tialamide
1-[(5-chloro-2-oxo-benzothiazol-3-yl)-acetyl]-4-(2-hydroxy-ethyl)-piperazine
Tiaramide [INN:BAN]
RHC 2592A
Tiaramidum [INN-Latin]
EINECS 251-083-7
3-[4-(2-hydroxyethyl)-1-piperazinyl]carbonylmethyl-5-chloro-2-benzothiazolinone

Chemical & Physical Properties

[ Density]:
1.432g/cm3

[ Boiling Point ]:
605.8ºC at 760mmHg

[ Molecular Formula ]:
C15H18ClN3O3S

[ Molecular Weight ]:
355.84000

[ Flash Point ]:
320.2ºC

[ Exact Mass ]:
355.07600

[ PSA ]:
94.02000

[ LogP ]:
0.72870

[ Index of Refraction ]:
1.64

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL7047000
CHEMICAL NAME :
1-Piperazineethanol, 4-((5-chloro-2-oxo-3-benzothiazolinyl)acetyl)-
CAS REGISTRY NUMBER :
32527-55-2
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H18-Cl-N3-O3-S
MOLECULAR WEIGHT :
355.87

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 107,28,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
564 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 107,28,1987

Synthetic Route

Precursor & DownStream


Related Compounds

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