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32527-55-2

32527-55-2 structure
32527-55-2 structure
  • Name: Tiaramide
  • Chemical Name: 5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]-1,3-benzothiazol-2-one
  • CAS Number: 32527-55-2
  • Molecular Formula: C15H18ClN3O3S
  • Molecular Weight: 355.84000
  • Catalog: API Antiallergic Allergic reaction medium blocker
  • Create Date: 2018-02-25 08:00:00
  • Modify Date: 2024-01-21 10:10:03

Name 5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]-1,3-benzothiazol-2-one
Synonyms Tiaramida [INN-Spanish]
USV 2592
5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]-3H-benzothiazol-2-one
TIARAMIDE
5-chloro-3-[4-(2-hydroxyethyl)-1-piperazinyl]carbonylmethyl-2-benzothiazolinone
tialamide
1-[(5-chloro-2-oxo-benzothiazol-3-yl)-acetyl]-4-(2-hydroxy-ethyl)-piperazine
Tiaramide [INN:BAN]
RHC 2592A
Tiaramidum [INN-Latin]
EINECS 251-083-7
3-[4-(2-hydroxyethyl)-1-piperazinyl]carbonylmethyl-5-chloro-2-benzothiazolinone
Density 1.432g/cm3
Boiling Point 605.8ºC at 760mmHg
Molecular Formula C15H18ClN3O3S
Molecular Weight 355.84000
Flash Point 320.2ºC
Exact Mass 355.07600
PSA 94.02000
LogP 0.72870
Index of Refraction 1.64

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL7047000
CHEMICAL NAME :
1-Piperazineethanol, 4-((5-chloro-2-oxo-3-benzothiazolinyl)acetyl)-
CAS REGISTRY NUMBER :
32527-55-2
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H18-Cl-N3-O3-S
MOLECULAR WEIGHT :
355.87

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 107,28,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
564 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 107,28,1987

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32527-55-2 structure

32527-55-2

Literature: Fujisawa Pharmaceutical Co., Ltd. Patent: US4242507 A1, 1980 ;
Precursor  3

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