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(1R,2S,5S,6S)-BICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID, 2-AMINO-6-FLUORO-4-OXO-

Names

[ CAS No. ]:
321963-33-1

[ Name ]:
(1R,2S,5S,6S)-BICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID, 2-AMINO-6-FLUORO-4-OXO-

[Synonym ]:
Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-6-fluoro-4-oxo-, (1R,2S,5S,6S)-
(1R,2S,5S,6S)-2-Amino-6-fluoro-4-oxobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
MGS-0028
YMS878LR7I

Biological Activity

[Description]:

MGS0028 is a selective metabotropic glutamate 2/3 (mGlu2/3) receptor agonist. MGS0028 can be used for psychiatric disorders research[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR
Research Areas >> Neurological Disease

[Target]

mGlu2 Receptor

mGluR3R


[References]

[1]. Yukio Ago, et al. The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide. Behav Pharmacol. 2013 Feb;24(1):74-7.  

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
438.4±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H8FNO5

[ Molecular Weight ]:
217.151

[ Flash Point ]:
218.9±28.7 °C

[ Exact Mass ]:
217.038651

[ LogP ]:
-1.98

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.613

Related Compounds

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