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6-Methoxyindole

Names

[ CAS No. ]:
3189-13-7

[ Name ]:
6-Methoxyindole

[Synonym ]:
indole, 6-methoxy-
EINECS 221-689-6
6-methoxy-indole
5-Methoxyindole,~
6-MeO-indole
6-Methoxyindole
Methoxyindole
6-Methoxy-1H-indole
6-methoxylindole
MFCD00022780
1H-Indole, 6-methoxy-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
297.8±13.0 °C at 760 mmHg

[ Melting Point ]:
90-92 °C(lit.)

[ Molecular Formula ]:
C9H9NO

[ Molecular Weight ]:
147.174

[ Flash Point ]:
109.2±10.1 °C

[ Exact Mass ]:
147.068420

[ PSA ]:
25.02000

[ LogP ]:
2.00

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.637

[ Storage condition ]:
Keep Cold

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Precursor & DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.

J. Med. Chem. 54 , 5320, (2011)

Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO) is an important mechanism of peripheral immune tolerance contributing to tumoral immune resistance. IDO inhibition is thus an active...

Discovery of a novel class of PPARdelta partial agonists.

Bioorg. Med. Chem. Lett. 18 , 5018, (2008)

Anthranilic acid GW9371 was identified as a novel class of PPARdelta partial agonist through high-throughput screening. The design and synthesis of SAR analogues is described. GSK1115 and GSK7227 show...

Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach.

J. Med. Chem. 52 , 4941, (2009)

BPR0L075 (2) is a potential anticancer drug candidate designed from Combretastatin A-4 (1) based on the bioisosterism principle. Metabolites of 2, proposed from in vitro human microsome studies, were ...


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