JNJ-2408068

Names

[ Name ]:
JNJ-2408068

[Synonym ]:
unii-ab821dl88a

Biological Activity

[Description]:

JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> RSV

[Target]

RSV-A

RSV-B

[References]

[1]. Wyde PR, et al. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov;60(3):221-31.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₀N₆O

[ Molecular Weight ]:
394.51300

[ Exact Mass ]:
394.24800

[ PSA ]:
95.46000

[ LogP ]:
2.69710

JNJ-2408068

Names

Biological Activity

Chemical & Physical Properties

Related Compounds