m-PEG2-Amine

Names

[ Name ]:
m-PEG2-Amine

[Synonym ]:
2-(2-Methoxyethoxy)ethanamine
2-(2-methoxy-ethoxy)-ethylamine
Ethylamine, 2-(2-methoxyethoxy)-,
Ethanamine,2-(2-methoxyethoxy)
2-(2-methoxyethoxy)ehthylamine
Ethylamine,2-(2-methoxyethoxy)
2-(2-methoxyethoxy)-ethanamine
tris-3,6-dioxaheptylamine
1-(2-aminoethoxy)-2-methoxyethane
methyletherdiethyleneglycol amine
Ethanamine, 2-(2-methoxyethoxy)-
3,6-dioxa-heptylamine

Biological Activity

[Description]:

m-PEG2-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Sander Sebastiaan Van Berkel, et al. Lieurs à sulfamide améliorés pour une utilisation dans des bioconjugués. WO2017137423A1.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
163.7±15.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₁₃NO₂

[ Molecular Weight ]:
119.162

[ Flash Point ]:
54.1±27.7 °C

[ Exact Mass ]:
119.094627

[ PSA ]:
44.48000

[ LogP ]:
-1.01

[ Vapour Pressure ]:
2.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.420

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
C

[ RIDADR ]:
3265.0

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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