Isobavachin

Names

[ Name ]:
Isobavachin

[Synonym ]:
4',7-dihydroxy-8-prenylflavanone
(+-)-6-chloro-7
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-, (2S)-
C16H16ClNO2
SK&6-Chlor-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin
(2S)-7-Hydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
6-chloro-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol
6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol
8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine
1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-1-phenyl
8-prenylliquiritigenin
8-dimethylallylliquiritigenin
6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Biological Activity

[Description]:

Isobavachin, an antioxidant isaolated from Psoralea morisiana with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Wang DY, et al. Promoting effects of isobavachin on neurogenesis of mouse embryonic stem cells were associated with protein prenylation. Acta Pharmacol Sin. 2011 Apr;32(4):425-32.

[2]. Antonella Rosa, et al. Antioxidant properties of extracts and compounds from Psoralea morisiana. European Journal of Lipid Science and Technology. 2005.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
558.3±50.0 °C at 760 mmHg

[ Melting Point ]:
187-188℃

[ Molecular Formula ]:
C₂₀H₂₀O₄

[ Molecular Weight ]:
324.370

[ Flash Point ]:
202.1±23.6 °C

[ Exact Mass ]:
324.136169

[ PSA ]:
66.76000

[ LogP ]:
4.85

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
2-8C

Safety Information

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%