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2'-C-Methyluridine

Names

[ CAS No. ]:
31448-54-1

[ Name ]:
2'-C-Methyluridine

[Synonym ]:
2'-C-Methyluridine
BCX-4018
Uridine,2'-C-methyl
2'-methyluridine
Uridine, 2'-C-methyl-
2'-C-methyl uridine
1-((2R,3R,4R,5R)-TETRAHYDRO-3,4-DIHYDROXY-5-(HYDROXYMETHYL)-3-METHYLFURAN-2-YL)PYRIMIDINE-2,4(1H,3H)-DIONE

Biological Activity

[Description]:

2'-C-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.  

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Melting Point ]:
110-112ºC

[ Molecular Formula ]:
C10H14N2O6

[ Molecular Weight ]:
258.23

[ Exact Mass ]:
258.085175

[ PSA ]:
124.78000

[ LogP ]:
-0.85

[ Index of Refraction ]:
1.615

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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