o-3M3FBS

Names

[ Name ]:
o-3M3FBS

[Synonym ]:
HMS3268M14
O-3M3FBS
Tocris-1942

Biological Activity

[Description]:

o-3M3FBS is the negative control of m-3M3FBS. o-3M3FBS inhibits inward and outward currents via mechanisms independent of PLC acting in an antagonistic manner. In contrast, o-3M3FBS also causes an increase in [Ca2+]i in an agonistic manner[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vivo]

o-3M3FBS (10 μM) decreases AUC from 1058±189 g/min in control (in the presence of TTX) to 840±134 g/min. Higher concentration of o-3M3FBS (25 μM) further decreases AUC to 457±59 g/min[1].

[References]

[1]. Dwyer L, et al. Phospholipase C-independent effects of 3M3FBS in murine colon. Eur J Pharmacol. 2010;628(1-3):187-194.

Chemical & Physical Properties

[ Density]:
1.316g/cm3

[ Boiling Point ]:
424.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₆H₁₆F₃NO₂S

[ Molecular Weight ]:
343.36400

[ Flash Point ]:
210.4ºC

[ Exact Mass ]:
343.08500

[ PSA ]:
54.55000

[ LogP ]:
5.58520

[ Index of Refraction ]:
1.547

Related Compounds

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