8-PIP-cAMP

Names

[ Name ]:
8-PIP-cAMP

[Synonym ]:
8-Piperidinoadenosine 3',5'-monophosphate sodium salt
8-PIP-cAMP
8-Piperidinoadenosine 3 inverted exclamation marka,5 inverted exclamation marka-monophosphate sodium salt
8-Piperidinoadenosine 3',5'-monophosphate
8-Piperidino-cyclicAMP
Cyclic 8-piperidino-3',5'-AMP

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₂₀N₆NaO₆P

[ Molecular Weight ]:
434.31900

[ Exact Mass ]:
434.10800

[ PSA ]:
170.72000

[ LogP ]:
1.25730

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosis.

Cell Death Dis. 4 , e516, (2013)

We show that cyclic AMP (cAMP) elevating agents protect blasts from patients with acute promyelocytic leukemia (APL) against death induced by first-line anti-leukemic anthracyclines like daunorubicin ...

8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanisms.

PLoS ONE 6(6) , e20785, (2011)

Cyclic AMP (cAMP) inhibits the proliferation of several tumor cells. We previously reported an antiproliferative effect of PKA I-selective cAMP analogs (8-PIP-cAMP and 8-HA-cAMP) on two human cancer c...

Related Compounds

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