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MMP3 inhibitor 1

Names

[ CAS No. ]:
312930-75-9

[ Name ]:
MMP3 inhibitor 1

Biological Activity

[Description]:

MMP3 inhibitor 1 is a potent and highly selective MMP-3 inhibitor with an IC50 of 1 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

[Target]

MMP-3:1 nM (IC50)

MMP-2:529 nM (IC50)

MMP-9:2420 nM (IC50)

MMP-1:14000 nM (IC50)

MMP-14:20100 nM (IC50)


[In Vitro]

MMP3 inhibitor 1 (Compound 27) inhibits MMP-1, MMP-2, MMP-9, and MMP-14 with IC50s of 14000, 529, 2420, and 20100 nM, respectively[1].

[References]

[1]. Whitlock GA, et al. A novel series of highly selective inhibitors of MMP-3. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6750-3.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H31N3O6S

[ Molecular Weight ]:
477.57


Related Compounds