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Bradykinin potentiator B

Names

[ CAS No. ]:
30892-86-5

[ Name ]:
Bradykinin potentiator B

[Synonym ]:
bradykinin potentiator b
Pyr-GLPPRPKIPP

Biological Activity

[Description]:

Bradykinin potentiator B (Bradykinin potentiating peptide B) is venom of Agkistrodon halys blomhoffi. Bradykinin potentiator B is a potent ACE inhibitor. Bradykinin potentiator inhibits the activity of bradykinin inhibitory peptidase[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

[References]

[1]. Kato H, et, al. Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. Biochemistry. 1971 Mar 16;10(6):972-80.   

[2]. Tom B, et, al. Bradykinin potentiation by ACE inhibitors: a matter of metabolism. Br J Pharmacol. 2002 Sep;137(2):276-84.  

Chemical & Physical Properties

[ Density]:
1.48g/cm3

[ Molecular Formula ]:
C56H91N15O13

[ Molecular Weight ]:
1182.41000

[ Exact Mass ]:
1181.69000

[ PSA ]:
401.37000

[ LogP ]:
1.70850

[ Index of Refraction ]:
1.684

Related Compounds