3,3'-Diethylthiatricarbocyanine iodide
Names
[ CAS No. ]:
3071-70-3
[ Name ]:
3,3'-Diethylthiatricarbocyanine iodide
[Synonym ]:
3,3'-diethyl-2,2'-thiadicarbocyanine iodide
3-Ethyl-2-[7-[3-ethyl-2(3H)-benzothiazolylidene]-1,3,5-heptatrienyl]benzothiazolium Iodide
DTTC IODIDE
3,3'-Diethylthiatricarbocyanine Iodide
THIATRICARBOCYANINE IODIDE,3,3'-DIETHYL
oliumiodide
DTTCI
NK-126
AURORA KA-295
MFCD00041994
3,3'-diethylthiatricarbocyanine
diethylthiatricarbocyanine iodide
3,3'-DIETHYL-2,2'-THIATRICARBOCYANINE IODIDE
1,7-bis-(3-ethyl-benzothiazol-2-yl)-heptamethinium,iodide
DTTC
EINECS 221-342-9
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Melting Point ]:
211ºC (dec.)(lit.)
[ Molecular Formula ]:
C25H25IN2S2
[ Molecular Weight ]:
544.51400
[ Exact Mass ]:
544.05000
[ PSA ]:
65.29000
[ LogP ]:
3.13620
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DL7045000
- CHEMICAL NAME :
- Benzothiazolium, 3-ethyl-2-(7-(3-ethyl-2-benzothiazolinylidene)-1,3,5- heptatrienyl)-, iodide
- CAS REGISTRY NUMBER :
- 3071-70-3
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C25-H25-N2-S2.I
- MOLECULAR WEIGHT :
- 544.54
- WISWESSER LINE NOTATION :
- T56 BNYSJ B2 CU2U2U2U1- CT56 BK DSJ B2 &I
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,897,1967
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26;S36/S37
[ RIDADR ]:
UN 2811
[ WGK Germany ]:
3
[ RTECS ]:
DL7045000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
Synthetic Route
Articles
J. Med. Chem. 52 , 3539-47, (2009)
A structure-activity relationship for symmetrical cyanine inhibitors of human tau aggregation was elaborated using a filter trap assay. Antagonist activity depended on cyanine heterocycle, polymethine...
Three-dimensional fluorescence lifetime tomography.Med. Phys. 32(4) , 992-1000, (2005)
Near-infrared fluorescence tomography using molecularly targeted lifetime-sensitive, fluorescent contrast agents have applications for early-stage cancer diagnostics. Yet, although the measurement of ...
Ionic dependence of membrane potential and glutamate receptor-linked responses in synaptoneurosomes as measured with a cyanine dye, DiS-C2-(5).J. Neurochem. 48(2) , 552-9, (1987)
Membrane potentials of particles present in a subcellular brain preparation, called synaptoneurosomes, have been monitored by measurement of changes in the absorbance of a cyanine dye, DiS-C2-5. The m...