2-(Trifluoromethyl)phenylacetic acid
Names
[ CAS No. ]:
3038-48-0
[ Name ]:
2-(Trifluoromethyl)phenylacetic acid
[Synonym ]:
ortho-(trifluoromethyl)phenylacetic acid
EINECS 207-093-9
2-(Trifluoromethyl)benzeneacetic acid
QV1R BXFFF
2-(2'-trifluoromethylphenyl)acetic acid
2-[2-(Trifluoromethyl)phenyl]acetic acid
2-(Trifluoromethyl)phenylacetic acid
MFCD00004327
[2-(Trifluoromethyl)phenyl]acetic acid
(a,a,a-trifluoro-o-tolyl)acetic acid
Benzeneacetic acid, 2-(trifluoromethyl)-
(α,α,α-Trifluoro-o-tolyl)acetic acid
o-(Trifluoromethyl)phenylacetic acid
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
249.9±35.0 °C at 760 mmHg
[ Melting Point ]:
107-110 °C(lit.)
[ Molecular Formula ]:
C9H7F3O2
[ Molecular Weight ]:
204.146
[ Flash Point ]:
105.0±25.9 °C
[ Exact Mass ]:
204.039810
[ PSA ]:
37.30000
[ LogP ]:
2.08
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.475
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Med. Chem. 35 , 2040, (1992)
Stimulation of platelets activates GPIIbIIIa, the heterodimeric integrin receptor, to bind fibrinogen (Fg), which results in platelet aggregation. GPIIbIIIa/Fg binding inhibitors are potentially suita...
Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors.J. Med. Chem. 33 , 1892, (1990)
A series of 2,6-disubstituted 4-(2-arylethenyl)phenols with potent human neutrophil 5-lipoxygenase (5-LO) inhibiting activity (IC50S in the 10(-7) M range) and weaker human platelet cyclooxygenase (CO...