2,8-Dihydroxyadenine

Names

[ Name ]:
2,8-Dihydroxyadenine

[Synonym ]:
2,8-Dihydroxyadenine
6-Amino-2,8-dihydroxypurine
Dimethyloctanoic acid
6-amino-1,7-dihydro-3H-purine-2,8-dione
2,8-Dioxyadenine
6-Amino-1,7-dihydro-3H-purin-2,8-dion
dimethyloctanoate
EINECS 250-158-1
6-amino-1H-purine-2,8(3H,7H)-dione

Biological Activity

[Description]:

2,8-Dihydroxyadenine, an endogenous metabolite, can cause the formation of urinary crystals and kidney stones. 2,8-Dihydroxyadenine can be used to diagnose adenine phosphoribosyltransferase (APRT) deficiency[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Ceballos-Picot I, et, al. 2,8-Dihydroxyadenine urolithiasis: a not so rare inborn error of purine metabolism. Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):241-52.

[2]. Sreejith P, et, al. 2, 8 Dihydroxyadenine urolithiasis: A case report and review of literature. Indian J Nephrol. 2009 Jan;19(1):34-6.

Chemical & Physical Properties

[ Density]:
2.52g/cm3

[ Boiling Point ]:
852.7ºC at 760mmHg

[ Melting Point ]:
>300 °C (dec.) (lit.)

[ Molecular Formula ]:
C₅H₅N₅O₂

[ Molecular Weight ]:
167.13

[ Flash Point ]:
469.5ºC

[ Exact Mass ]:
167.04400

[ PSA ]:
120.94000

[ Index of Refraction ]:
2.156

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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