RL-0070933

Names

[ CAS No. ]:
301326-41-0

[ Name ]:
RL-0070933

[Synonym ]:
Benzoic acid, 4-hydroxy-, 2-([1,1'-biphenyl]-4-ylmethylene)hydrazide

Biological Activity

[Description]:

RL-0070933 is a potent smo cilial modulator with an EC50 value of 0.02 µM. RL-0070933 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> Smo
Research Areas >> Cancer
Signaling Pathways >> Stem Cell/Wnt >> Hedgehog

[References]

[1]. Yu Wang, et al. Modulators of hedgehog signaling pathway. US20130274233A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H16N2O2

[ Molecular Weight ]:
316.35

Related Compounds