N,N-Dimethyldodecanamide
Names
[ CAS No. ]:
3007-53-2
[ Name ]:
N,N-Dimethyldodecanamide
[Synonym ]:
N,N-dimethyl dodecanamide
DODECANAMIDE,N,N-DIMETHYL
N,N-dimethyldodecanoamide
Hallcomid M 12
N,N-dimethyldodecylamide
N,N-Dimethyllauramide
N,N-DIMETHYLDODECANAMIDE
EINECS 221-117-5
N,N-Dimethyldodecamide
Lauric acid N,N-dimethylamide
Lauryl N,N-dimethylamide
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
0.87
[ Boiling Point ]:
284.9ºC at 760 mmHg
[ Molecular Formula ]:
C14H29NO
[ Molecular Weight ]:
227.38600
[ Flash Point ]:
106ºC
[ Exact Mass ]:
227.22500
[ PSA ]:
20.31000
[ LogP ]:
3.99550
[ Index of Refraction ]:
1.447
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JR2050000
- CHEMICAL NAME :
- Dodecanamide, N,N-dimethyl-
- CAS REGISTRY NUMBER :
- 3007-53-2
- BEILSTEIN REFERENCE NO. :
- 1769950
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C14-H29-N-O
- MOLECULAR WEIGHT :
- 227.44
- WISWESSER LINE NOTATION :
- 11VN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 32,539,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea Blood - hemorrhage
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 32,539,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 32,539,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea Blood - hemorrhage
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 32,539,1971
Safety Information
[ Symbol ]:
GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H410
[ Precautionary Statements ]:
P273-P501
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
N: Dangerous for the environment;
[ Risk Phrases ]:
R50/53
[ Safety Phrases ]:
60-61
[ RIDADR ]:
UN 3082
[ WGK Germany ]:
3
[ RTECS ]:
JR2050000
[ HS Code ]:
2924199090
Synthetic Route
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Pharm. Sci. 82 , 214-219, (1993)
A series of novel dermal penetration enhancers, esters and amides of clofibric acid, was synthesized. The permeation parameters and skin retention of two steroids (hydrocortisone-21-acetate and betame...